Investigation of Ethyl Acetate Soluble Pro an thocyanidins in the Inflorescence of Cocos nucifera L.

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dc.contributor.authorPadumadasa, C.
dc.contributor.authorDharmadana, D.
dc.contributor.authorAbeysekera, A.M.
dc.contributor.authorThammitiyagodage, M.G.
dc.date.accessioned2017-10-23T05:10:54Z
dc.date.available2017-10-23T05:10:54Z
dc.date.issued2015
dc.description.abstractAttacheden_US, si_LK
dc.description.abstractThe immature inflorescence of Cocos nucifera L. variety aurantiaca is used in Ayurveda for the treatment of menorrhagia in Sri Lanka. Preliminary phytochemical screening revealed that immature inflorescence predominantly contains proanthocyanidins. TTie ethyl acetate soluble proanthocyanidin (EASPA' f action obtained from an acetone/water (7:3) extract of the immature inflorescence was effectively purified and separated from other phenolic compounds by chromatography on sephadex LH-20. EASPA has been fully characterized by chromatographic, spectroscopic and spectrometric methods. Acid catalyzed cleavage followed by TLC indicated that EASPA is composed of (epi)catechin and (epi)afeelechin monomeric units while thiolysis followed by ‘H and 13C NMR spectroscopy revealed the monomers to be the epi-isomers. I3C NMR studies of EASPA showed signals characteristic for epicatechin units indicating that EASPA is composed mainly of epicatechin units. Confirming these epicatechin oligomers with degrees of polymerization ranging from 2-5 and mixed oligomers, epicatechin-epiafzelechin dimer and epicatechin-epicatechin-epiafzelechin trimer were observed by ESI-MS.
dc.identifier.citationPadumadasa, C., Dharmadana, D., Abeysekera, A.M., Thammitiyagodage, M.G. (2015). "Investigation of Ethyl Acetate Soluble Pro an thocyanidins in the Inflorescence of Cocos nucifera L.", Journal of Pharmacognosy and Phytochemistry, Vol.4 (2), pp. 107-111en_US, si_LK
dc.identifier.issn2278-4136
dc.identifier.issn2349-8234
dc.identifier.urihttp://dr.lib.sjp.ac.lk/handle/123456789/6017
dc.language.isoen_USen_US, si_LK
dc.publisherJournal of Pharmacognosy and Phytochemistryen_US, si_LK
dc.subjectCocos nucifera inflorescenceen_US, si_LK
dc.subjectproanthocyanidinen_US, si_LK
dc.subjectepicatechinen_US, si_LK
dc.subjectepiafzelechinen_US, si_LK
dc.subjectthiolysisen_US, si_LK
dc.titleInvestigation of Ethyl Acetate Soluble Pro an thocyanidins in the Inflorescence of Cocos nucifera L.en_US, si_LK
dc.typeArticleen_US, si_LK

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