MARINE BACTERIA AND FUNGI AS SOURCES FOR BIOACTIVE COMPOUNDS PRESENT STATUS AND FUTURE TRENDS.

Abstract

Marine organisms undergo a vast range of chemical and physical conditions in the marine environment, thus a high diversity is reported in the bioactive compounds they produce. With the development of marine biotechnology, a considerable number of researches are focused on marine bacteria and fungi-derived bioactive compounds. As a result, marine bacteria and fungi are ranked on the top of the hierarchy of all organisms, as they are responsible for producing a wide range of bioactive secondary metabolites with potential pharmaceutical applications. Thus, they have the potential to provide future drugs against important diseases, such as cancer, a range of viral diseases, malaria, and inflammations. This review aims at describing some of the most highly cited reviews of the last decade on marine bacteria and fungi -derived bioactive compounds and the most promising substances extracted and isolated from these for pharmaceutical applications.