Effect of Sri Lankan Black Tea Brew (Camellia sinensis) on Hexabarbital Induced Sleep in Mice

dc.contributor.authorRatnasooriya, W.D.
dc.contributor.authorFernando, T.S.P.
dc.contributor.authorMadubashini, P.P.
dc.date.accessioned2013-05-09T08:09:58Z
dc.date.available2013-05-09T08:09:58Z
dc.date.issued2006
dc.date.published2006
dc.description.abstractPresent study examined the effect of warm black tea brew/ infusion (BTB) of Camellia sinensis (L.) O. Kuntze (family: Theaceae) on sleep. The above was tested in hexabarbital induced sleep model in mice using three doses (equivalent to 1_5.3. and 9 cups. 1 cup 170 ml) of Sri Lankan high grown Dust grade No: 1 black tea or a single dose (equivalentto 9 cups) of green tea brew CGTB)ofJapanese and Chinese varieties. The results showed that black tea brew (BTB) significantly (P < 0.05) and dose-dependently prolonged the onset and shortened the duration of sleep. A simi lar effect was elicited with the high dose of GTBs but w~th a higher efficacy. Decaffeination of 8TB suppressed the effects on the onset of sleep induced by the normal 8TB. It is concluded that Sri Lankan black tea disrupts sleep in mice possibly via dopaminergic, serotoninergic and nerve stimulant mechanisms.en_US
dc.identifier.citationRatnasooriya, W.D., Fernando, T.S.P., & Madubashini, P.P. (2006). Effect of Sri Lankan Black Tea Brew (Camellia sinensis) on Hexabarbital Induced Sleep in Mice. Vidyodaya Journal of Science, 13, 109-114.en-US
dc.identifier.urihttp://dl.sjp.ac.lk/dspace/handle/123456789/1048
dc.language.isoenen_US
dc.subjectCamellia sinensisen_US
dc.subjectSleepen_US
dc.subjectTheanineen_US
dc.subjectCaffeineen_US
dc.subjectTeaen_US
dc.subjectDustgradeen_US
dc.titleEffect of Sri Lankan Black Tea Brew (Camellia sinensis) on Hexabarbital Induced Sleep in Miceen_US
dc.typeArticleen_US

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