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Gene Flow Patterns among Aedes aegypti (Diptera: Culicidae) Populations in Sri Lanka

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dc.contributor.author Fernando, H.S.D
dc.contributor.author Hapugoda, M
dc.contributor.author Perera, R
dc.contributor.author Black IV, W. C
dc.contributor.author De Silva, B. G. D. N. K.
dc.date.accessioned 2022-09-13T11:06:26Z
dc.date.available 2022-09-13T11:06:26Z
dc.date.issued 2020
dc.identifier.citation Fernando, H.S.D., et al. (2020). Gene Flow Patterns among Aedes aegypti (Diptera: Culicidae) Populations in Sri Lanka. Insects 2020, 11, 169. en_US
dc.identifier.uri http://dr.lib.sjp.ac.lk/handle/123456789/12211
dc.description.abstract In Sri Lanka, dengue is the most serious arboviral disease. Recent increases in dengue cases suggest a higher infection rate and spread of the disease to new areas. The present study exploresgeneflowpatternsofAe. aegypti,themainvectorofdenguedisease,among10collectionsites includingmajorportsandinlandcitiesusingvariationsat11microsatelliteloci. Discriminantanalysis of principal components (DAPC) and k-means clustering estimated eight genetic clusters. Analysis of Molecular Variance (AMOVA) estimated equal variances among cities and among collections in Colombo, Sri Lanka. Significant evidence, although weak, was detected for isolation by distance. Analysis of gene flow rates and directions using MIGRATE-n indicated that populations throughout the island served as a source of immigrants for Colombo with abundant gene flow among major commercialcitiesinSriLanka,whichappeartoreceivemigrantmosquitoesfromthroughoutSriLanka. The observed patterns probably arise through human movement of Ae. aegypti during commerce fromthroughoutSriLankaintoColomboincreasingtheriskofspread. Thepatternsuncoveredinthis studyaresignificantforglobalhealthasSriLankaissituatedalongakeyinternationalshippingroute. en_US
dc.language.iso en en_US
dc.publisher Insects en_US
dc.subject Aedes aegypti; population structure; gene flow patterns; Sri Lanka en_US
dc.title Gene Flow Patterns among Aedes aegypti (Diptera: Culicidae) Populations in Sri Lanka en_US
dc.type Article en_US


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