Antireproductive Effects in Male Rats Exposed to Methamidophos

dc.contributor.author	Peiris, L.D.C.
dc.contributor.author	Jayatunga, Y.N.A.
dc.contributor.author	Ratnasooriya, W.D.
dc.date.accessioned	2016-12-01T06:23:55Z
dc.date.available	2016-12-01T06:23:55Z
dc.date.issued	1995
dc.identifier.citation	Peiris, L.D.C., Jayatunga, Y.N.A., & Ratnasooriya, W.D. (1995). Ant Reproductive Effects in Male Rats Exposed to Methamidophos. Ceylon Journal of Science (Biological Sciences), 24(2), 53-59.	en_US, si_LK
dc.identifier.issn	2513-2814
dc.identifier.uri	http://dr.lib.sjp.ac.lk/handle/123456789/3497
dc.description.abstract	This study examined the reproductive effects of methamidophos, an organophosphorus pesticide on male rats following sub-chronic oral administration (in 3 alternate days). The doses tested were 1.8750 and 0.9375 mg kg"1 day"1 and the reproductive effects were investigated upto 28 - 35 days post-treatment. The results show that both doses of methamidophos inhibited libido in a reversible fashion lasting upto 28 – 35 days. This effect on libido was accompanied by marked depressions in food and water intake, body weight and by cholinergic intoxication. Furthermore, the treatment was reprotoxic: decreased testicular interstitial fluid volume, seminiferous tubular diameter and reduction in motility and numbers of cauda epididymal sperm. Based on these data it is concluded that methamidophos could be detrimental to the sexuality and fertility of men who are constantly exposed to it.	en_US, si_LK
dc.language.iso	en	en_US, si_LK
dc.publisher	University of Peradeniya, Peradeniya.	en_US, si_LK
dc.title	Antireproductive Effects in Male Rats Exposed to Methamidophos	en_US, si_LK
dc.type	Article	en_US, si_LK