Comparative cytotoxicity of selected cyanotoxins on Human Embryonic Kidney (HEK 293) and Human Kidney Adenocarcinoma (ACHN) Cells.

dc.contributor.author	Piyathilaka, P.C.
dc.contributor.author	Tennekoon, K.H.
dc.contributor.author	De Silva, N.K.
dc.contributor.author	Manage, P.M.
dc.date.accessioned	2017-10-26T05:44:54Z
dc.date.available	2017-10-26T05:44:54Z
dc.date.issued	2016
dc.identifier.citation	Piyathilaka, P.C., Tennekoon, K.H., De Silva, N.K., Manage, P.M. (2016). "Comparative cytotoxicity of selected cyanotoxins on Human Embryonic Kidney (HEK 293) and Human Kidney Adenocarcinoma (ACHN) Cells.", ISOI Journal Of Microbiology, Biotechnology And Food Science, Vol.2 (1), pp. 45-49	en_US, si_LK
dc.identifier.issn	2395-6887
dc.identifier.uri	http://dr.lib.sjp.ac.lk/handle/123456789/6162
dc.description.abstract	Attached	en_US, si_LK
dc.description.abstract	The aim of present study was to evaluate the cytotoxic effects of some selected cyanotoxins namely, MC-LR, MC-RR, MC-LF, MC-LW and Nodularin on normal human kidney cells (HEK-293) and human kidney adenocarcinoma cells (ACHN). Cells were exposed to different concentrations of (1.0-200 pM ) cyanotoxin variants for 24 h and the cytotoxic effects were evaluated by Sulphorhodamine B (SRB) assay. Overall findings of the study demonstrate that cyanotoxins could cause cytotoxic effects on kidney cells. MC-LR was the most toxic while MC-LW was least toxic cyanotoxin on both cell types tested. MC-RR, MC-LF and Nodularin had moderate cytotoxicity on human renal cells.
dc.language.iso	en_US	en_US, si_LK
dc.publisher	ISOI Journal Of Microbiology, Biotechnology And Food Science	en_US, si_LK
dc.subject	Cytotoxicity	en_US, si_LK
dc.subject	ACHN cells	en_US, si_LK
dc.subject	HEK-293 cells	en_US, si_LK
dc.subject	SRB	en_US, si_LK
dc.subject	Cyanotoxins	en_US, si_LK
dc.title	Comparative cytotoxicity of selected cyanotoxins on Human Embryonic Kidney (HEK 293) and Human Kidney Adenocarcinoma (ACHN) Cells.	en_US, si_LK
dc.type	Article	en_US, si_LK