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Analysis of Clinical Features with Microscopy of Cutaneous Leishmanisis Suspected Patients Attending the Dermatology Clinic at General Hospital Hambanthota

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dc.contributor.author De Silva, L.D.G.G.
dc.contributor.author Somaratne, V.
dc.contributor.author Senaratne, S.
dc.contributor.author Vipuladasa, M.
dc.contributor.author Kahatapitiya, S.N.
dc.contributor.author De Silva, D.D.S.
dc.contributor.author Dissanayake, I.D.J.C.
dc.contributor.author Ranasinghe, S.
dc.contributor.author Wickremasinghe, R.
dc.date.accessioned 2017-11-02T15:45:13Z
dc.date.available 2017-11-02T15:45:13Z
dc.date.issued 2016
dc.identifier.citation De Silva, L.D.G.G., Somaratne, V., Senaratne, S., Vipuladasa, M., Kahatapitiya, S.N., De Silva, D.D.S., Dissanayake, I.D.J.C., Ranasinghe, S., Wickremasinghe, R. (2016). "Analysis of Clinical Features with Microscopy of Cutaneous Leishmanisis Suspected Patients Attending the Dermatology Clinic at General Hospital Hambanthota", Open University Research Sessions 2016 en_US, si_LK
dc.identifier.issn 2536-8893
dc.identifier.uri http://dr.lib.sjp.ac.lk/handle/123456789/6441
dc.description.abstract Attached en_US, si_LK
dc.description.abstract Cutaneous leishmaniasis (CL) is now an endemic disease, caused by Leishmania donavani Mon-37 strain in Sri Lanka CL in Sri Lanka is known to give a clinical spectrum. The parasite burden in different clinical presentations has not been assessed in detail yet. Therefore the aim of this study was to assess the parasite load with the clinical presentation of cutaneous leishmaniosis lesions of patients presenting to dermatology clinic in the Hambanthota General Hospital. Clinical presentations of the suspected CL lesions of 87 patients were examined and photographed with written informed consent. Clinical diagnosis was confirmed by detecting Leishman Donavan (LD) bodies in slit skin smear (SSS). Parasite count of SSS was obtained j in different clinical manifestations in accordance with the WHO grading by double blind method. A wide range of clinical presentations were observed; Clinical manifestations were categorized as papules, nodules, nodulo-ulcerative lesions, ulcers (dry/wet) and plaques. 49/87 clinically suspected lesions were positive by SSS. Most frequent clinical presentations were nodules (40%) and dry ulcers (34%). Duration of the lesions varied from 1-6 months (83.9%).The sites of the lesions were arm, leg, forearm, face, ear, neck, abdomen, and chest. All lesions were on exposed areas of the body. Mean parasite grading obtained according to WHO classification was as follows; Dry ulcers (3.5), plaques (3), Satellite lesions (3) nodules (2.25), Papules (2), wet ulcers (2), and Ulcerative nodules (1.25). Results of this study indicate that, the nodules and ulcers which are rich in LD bodies could be the main human parasite source for transmission in the community.
dc.language.iso en_US en_US, si_LK
dc.publisher Open University Research Sessions 2016 en_US, si_LK
dc.subject Cutaneous leishmaniosis en_US, si_LK
dc.subject Leishmania donavani en_US, si_LK
dc.subject Slit skin smears en_US, si_LK
dc.subject clinical presentation en_US, si_LK
dc.title Analysis of Clinical Features with Microscopy of Cutaneous Leishmanisis Suspected Patients Attending the Dermatology Clinic at General Hospital Hambanthota en_US, si_LK
dc.type Article en_US, si_LK


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