Comparative cytotoxicity of selected cyanotoxins on Human Embryonic Kidney (HEK 293) and Human Kidney Adenocarcinoma (ACHN) Cells.

Simple item page
dc.contributor.authorPiyathilaka, P.C.
dc.contributor.authorTennekoon, K.H.
dc.contributor.authorDe Silva, N.K.
dc.contributor.authorManage, P.M.
dc.date.accessioned2017-10-26T05:44:54Z
dc.date.available2017-10-26T05:44:54Z
dc.date.issued2016
dc.description.abstractAttacheden_US, si_LK
dc.description.abstractThe aim of present study was to evaluate the cytotoxic effects of some selected cyanotoxins namely, MC-LR, MC-RR, MC-LF, MC-LW and Nodularin on normal human kidney cells (HEK-293) and human kidney adenocarcinoma cells (ACHN). Cells were exposed to different concentrations of (1.0-200 pM ) cyanotoxin variants for 24 h and the cytotoxic effects were evaluated by Sulphorhodamine B (SRB) assay. Overall findings of the study demonstrate that cyanotoxins could cause cytotoxic effects on kidney cells. MC-LR was the most toxic while MC-LW was least toxic cyanotoxin on both cell types tested. MC-RR, MC-LF and Nodularin had moderate cytotoxicity on human renal cells.
dc.identifier.citationPiyathilaka, P.C., Tennekoon, K.H., De Silva, N.K., Manage, P.M. (2016). "Comparative cytotoxicity of selected cyanotoxins on Human Embryonic Kidney (HEK 293) and Human Kidney Adenocarcinoma (ACHN) Cells.", ISOI Journal Of Microbiology, Biotechnology And Food Science, Vol.2 (1), pp. 45-49en_US, si_LK
dc.identifier.issn2395-6887
dc.identifier.urihttp://dr.lib.sjp.ac.lk/handle/123456789/6162
dc.language.isoen_USen_US, si_LK
dc.publisherISOI Journal Of Microbiology, Biotechnology And Food Scienceen_US, si_LK
dc.subjectCytotoxicityen_US, si_LK
dc.subjectACHN cellsen_US, si_LK
dc.subjectHEK-293 cellsen_US, si_LK
dc.subjectSRBen_US, si_LK
dc.subjectCyanotoxinsen_US, si_LK
dc.titleComparative cytotoxicity of selected cyanotoxins on Human Embryonic Kidney (HEK 293) and Human Kidney Adenocarcinoma (ACHN) Cells.en_US, si_LK
dc.typeArticleen_US, si_LK

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
Comparative cytotoxicity of selected cyanotoxins on Human Embryonic Kidney (HEK 293) and Human Kidney Adenocarcinoma (ACHN) Cells..pdf
Size:
181.09 KB
Format:
Adobe Portable Document Format
Download

License bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

2016 - Applied